It includes five review
articles and two original papers that capture these new exciting aspects of
Wnts and the Wnt signaling pathways in the nervous system development and
disease. Changes of Wnt signaling components have been observed in Alzheimer's disease
and Parkinson's disease. Further understanding of the targets regulated by Wnts will inspire strategies
for the treatment and perhaps cure of developmental and neurodegenerative
conditions where Wnts play a central role.MNCLHD
Wednesday, September 03, 2014
Wnt Signalling Pathways
The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass
signals from outside of a cell through cell surface receptors to the inside of
the cell. A special issue of Developmental Neurobiology titled "Wnt Signaling Mechanisms in Development and Disease" is open access.
It includes five review
articles and two original papers that capture these new exciting aspects of
Wnts and the Wnt signaling pathways in the nervous system development and
disease. Changes of Wnt signaling components have been observed in Alzheimer's disease
and Parkinson's disease. Further understanding of the targets regulated by Wnts will inspire strategies
for the treatment and perhaps cure of developmental and neurodegenerative
conditions where Wnts play a central role.
It includes five review
articles and two original papers that capture these new exciting aspects of
Wnts and the Wnt signaling pathways in the nervous system development and
disease. Changes of Wnt signaling components have been observed in Alzheimer's disease
and Parkinson's disease. Further understanding of the targets regulated by Wnts will inspire strategies
for the treatment and perhaps cure of developmental and neurodegenerative
conditions where Wnts play a central role.
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