incorporate evidence from recent landmark clinical trials. There are a number of important changes:
- Severity of airflow obstruction via spirometry is no longer part of the severity classification system.
- Dual bronchodilatation with LABA/LAMA therapy is recommended for GOLD grades B and C.
- Inhaled corticosteroids should no longer be used as monotherapy in COPD.
- Pharmacotherapy for secondary pulmonary hypertension in the setting of COPD is not recommended.
- Oxygen therapy is also not recommended for COPD patients with no evidence of severe resting hypoxaemia.
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